Dapsone Alone Compared with Dapsone Plus Rifamcipin in Short-term Therapy of Lepromatous Leprosy
نویسندگان
چکیده
منابع مشابه
Low dose dapsone therapy in lepromatous leprosy.
U n der the conditions of this s tudy, dapsone in d oses of 5 mg and 10 mg daily when ad ministered to p atients with lepromat ous leprosy is an ineffe ctive therapy in terms of killing and elimin ation of My co. leprae from human skin and b one marrow . A real danger of facili tating the emergence of resistant bacilli exists . Therefore , un til there is more evidence from long term therapeuti...
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Aplastic anaemia associated with multidrug therapy (dapsone, rifampicin and clofazimine) in a patient with lepromatous leprosy ISABELA M. B. GOULART, ANA CLÁUDIA S. REIS, TATIANA M. N. DE REZENDE, AÉRCIO S. BORGES, MARCELO S. FERREIRA & SÉRGIO A. NISHIOKA State Reference Center for Sanitary Dermatology and Leprosy, Clinical Hospital, Faculty of Medicine, Federal University of Uberlândia, Minas ...
متن کاملMalaria, leprosy and dapsone.
Although the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous...
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While u nder treatment with'dapso ne for lepromatous leprosy , a 5 0-year-old male Greek Cypriot presented with multiple widespread lesions of a bizarre type, many of them freely ulceTating. Iinically and histologically, peripheral nerves were little affected, but biopsy s mples of skin and ulcers contained enormous numbers of leprosy bacilli. M ouse footpad inoculation of the bacilli from skin...
متن کاملEdito ria l C OMBINED THERAPY IN PRINCIPLE AND PRACTICE FOR THE C ONTROL OF DAPSONE RESIST ANCE The widespread emergence of dapsone-resistant strains of Mycobacterium leprae in patients with lepromatous leprosy who had been treated with dapsone
The widespread emergence of dapsone-resistant strains of Mycobacterium leprae in patients with lepromatous leprosy who had been treated with dapsone as monotherapy, is now fully accepted (WHO, 1 977). This growing problem of acquired (secondary) dapsone resistance among the large pool of dapsone treated lepromatous patients at risk, could be still more foreboding with the recent reports of new...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1977
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19770028